CHiP-GIS supports wide variety of cell-based and cell-free assays in experimental systems.
We have HTS-compatible instruments that supports a wide variety of detection modalities for assay measurements including: absorbance, fluorescence, time-resolved fluorescence, fluorescence polarization, fluorescence resonance energy transfer (FRET), time-resolved FRET and luminescence.
HTS/HCS based Functional Genomics
siRNA /miRNA/lncRNA Screens
Human siRNA whole genome and functional subsets - Silencer Select™
Mouse siRNA whole genome - Silencer Select™
Human miRNA mimics and inhibitor -Silencer Select™
Mouse miRNA mimics and inhibitor-Silencer Select™
Human Long Non Coding RNA - Silencer Select™
Human Whole genome arrayed shRNA –Version TRC 1.0, 1.5 and 2.0
Human Whole Genome arrayed ORF cDNA clones available for screen from Lifetech.
HTS/HCS based Chemical Genomics
CHiP-GIS has SMART collection of ~75,000 small molecules for target validation and lead discovery purposes.
For Target Validation and Re-purposes screens, we offer, Spectrum Collection(2400), Killer collection (160), LOPAC (1280), Anticancer (414), Kinase Inhibitor (417), Stem cell signalling compound (81), anti-diabetic compound library (32) and active Pfizer Scaffold (80).
For discovery sets, we offer novel scaffold (to enable Lead identification and optimisation) for your target based-phenotypic screens from Enamine Pharmacology Diversity Set (10240) and ChemDiv discovery sets (50,000).