CHiP-GIS Screening Fee



siRNA /shRNA Libraries


S.No siRNA libraries Price in SGD
1 Human test plates: one plate in triplicate of random human siRNAs/miRNAs 300
2 Mouse test plates: one plate in triplicate of random mouse siRNAs/miRNAs 300
3 Human siRNA pilot screen: 3 plates in triplicate 1200
4 Mouse siRNA pilot screen: 3 plates in triplicate 1200
5 Human siRNA whole genome 9500
6 Mouse siRNA whole genome 9200
7 Human mirVana mimic 950
8 Human mirVana inhibitor 950
9 Mouse mirVana mimic 950
10 Mouse mirVana inhibitor 950
11 Protein kinases - Human 900
12 GPCR – Human 600
13 Phosphatases – Human 300
14 Ion channels – Human 600
15 Protease – Human 600
16 Ubiquitin subset 1,2&3 – Human 900
17 Silencer Select Human Long non coding RNA 2000

Screening fees cover instrumentation usage associated with the number of assay plates. Test and pilot screens must be approved by facility staff before the rest of genome plates can be screened. Human and mouse rest of genome screening fees include cherrypicks from 100 genes (300 siRNAs). Human and mouse miRNA mimic and inhibitor screening fees include 30 cherrypicks.


Cost of hitpicks (Variable)


S.No shRNA libraries Price in SGD
1 shRNA human whole genome as 11 pools (format Plasmid) 11000
2 shRNA mouse whole genome as 21 pools (format Plasmid) 15000
3 Individual clones are available (glycerol stock) 20

Information for formatting and uploading data will be provided after your pilot screen is done. Once data is entered, directions will be provided for viewing data and submit wells of interest and hits.

  1. Human genome: 100 genes free (3 siRNAs/gene), then $10/gene; 250 genes max
  2. Human miRNA mimic or inhibitor: 30 free, then $10/target; 60 max
  3. Mouse genome: 100 genes free (3 siRNAs/gene), then $10/gene; 250 genes max
  4. Mouse miRNA mimic or inhibitor: 30 free, then $10/target; 60 max
  5. Human Long non coding siRNA : 30 free, then $10/target; 60 max

cDNA ORF clones/ expression ready libraries


S.No cDNA libraries Price in SGD
1 CCSB human Whole genome cDNA expression ready (arrayed /pool- glycerol stock) NA (through GIS PI as collaboration only)
2 Human ORF Lite - Life tech (arrayed - glycerol stock ) 50 / clone

Small molecule inhibitor and Libraries


Target Validation / re-purpose sets Number of compounds Price in SGD
MicroSource - Spectrum collection 2400 2100
MicroSource - Killer compounds 160 600
LOPAC - Library of Pharmacologically Active Compounds 1280 1500
SelleckChem - Anti-cancer library 414 900
SelleckChem - Kinase library 417 900
SelleckChem - Epigenetic library 151 900
MCE-GPCR Library 510 1200

Enamine - Discovery Sets Number of compounds Price in SGD
Enamine Pharmacology Diversity Set (PDS) 10240 5500

ChemDiv - Discovery Sets Number of compounds Price in SGD
Antiviral HBV-Targeted 12000 6000
Antiviral Library 10000 5500
CNS library 2500 3500
Anticancer Library - Major pathways 5000 4500
Natural-Product-Based Library 4000 3500
Developmental Pathway (like Hh/Wnt) Set 2000 2100
Cancer Stem Cells Targeted Library 2000 2100
PPI inhibitors (like Bcl2-Bax) Library 2000 2100
Epigenetics Library 2000 2100
KRAS, Raf, MEK, ERK-Targeted Library 2000 2100
Quiescent Cancer Cell Pathways Set 2000 2100
TK-Targeted Library 2000 2100
PKM2 Analogs 435 900
Metabolism_PKM2 Modulators 2065 2100

The compounds are arrayed in 384-well microtiter plates and are available for screening at 1mM and 0.1mM stock concentrations. The first and last two columns are empty on each plate. For details regarding Cherry picks, please contact facility personnel.